Documentation. Greener Alternative Principles. Boiling Point: 93C to 95C (0.1 hPa) Flash Point: 120C: Assay Percent Range: 98.5% min. Vapor pressure @ [34] Polyoxazolidones could find use as rigid, highly branched and solvent-resistant thermoset plastics in the electrical and electronics industry. . Shop Isosorbide dimethyl ether, 99%, Thermo Scientific at Fishersci.com English English; Change Country. Isosorbitol dimethyl ether (DMI) applied in cosmetics: can significantly enhance the effect of sunscreen, anti-wrinkle, freckle, acne, skin care and moisturizing, weight loss . This may take some time to load. for external use. Sealed in dry,Room Temperature form Liquid color Clear colorless to light yellow PH 7.0-8.0 (100g/l, H2O, 20) optical activity []21/D +96.1, c = 2 in chloroform Water Solubility Soluble in water. Dimethyl Isosorbide (Arlasolve DMI) can be used to aid penetration of actives into the skin. It also prevents dissolved actives from recrystallizing and thereby becoming useless to the skin. Green Chem., 2022,24, 4082 Chemical Hazard Irritant GHS Demand for bio-based solvents with a high boiling point, low viscosity, and negligible toxicity is increasing. This Thermo Scientific brand product was originally part of the Acros Organics product portfolio. It could in principle replace the bisphenol A, which was identified as xenoestrogen. CAS Number 5306-85-4 Molecular Formula C8H14O4 . and diagrams provided correct acknowledgement is given. ISOSORBIDE DIMETHYL ETHER CAS 5306-85-4 Integrity management, service first, best quality,ZSpharmac dedicated to serve you. [13], Esterification of isosorbide with fatty acids gives access to isosorbide monoesters, which are useful as detergents in household cleaners, dishwashing detergents, and cosmetic preparations, because of their properties as surfactant. 99% Purity: This allows to reach the minimum requirement of fire protection (class B2) with only 3% ISTP.[22]. Shop Isosorbide dimethyl ether, 99%, Thermo Scientific at Fishersci.ca Read more about how to correctly acknowledge RSC content. : 5306-85-4. ISOSORBIDE DIMETHYL ETHER Chemical Properties: Melting point-70C: Boiling point: 93-95 C0.1 mm Hg(lit.) Get the forecast for today, tonight & tomorrow's weather for Gunzenhausen, Bavaria, Germany. Furthermore it is known to use isosorbide derivatives as additives in various applications, like detergents, cleansers or cosmetic compositions. Windfinder specializes in wind, waves, tides and weather reports & forecasts for wind related sports like kitesurfing, windsurfing, surfing, sailing, fishing or paragliding. density 1.15 g/mL at 25 C(lit.) Demand for bio-based solvents with a high boiling point, low viscosity, and negligible toxicity is increasing. will be also provided by us. Flash Point(C) 116 C - closed cup. Pricing on 11kg size is in lieu of Customer Rewards Points or any other discount. However, the inherently lower reactivity of the secondary hydroxyl groups in isosorbide cause in comparison lower molecular weights and high residual contents of terephthalic acid, which leads to the insufficient chemical stability of the resulting polymers. The EWG VERIFIED mark means a product meets EWG's strictest criteria for transparency and health. A more efficient fibrillation of obtained pulp to nanocellulose was developed, leading to a promising potential of energy saving compared to the traditional bleaching pathway. It is a liquid possessing a low vapor pressure at room temperature and boiling point of 95C at 0.1 mm Hg. Boiling point : 93-95 C/0.1 mmHg Melting point : NA Solubility :---- Molecular Weight : 174.19 Density : 1.15 g/mL at 25 C Work has been carried by Uniquema using a hydrophilic active. Melting Point:-70.00 C. Please sign in to view account pricing and product availability. BOC Sciences provides a wide range of services to support the pharmaceutical industry through all stages of drug discovery including Custom Synthesis of those chemicals that are not in stock, Isotope Labeling Service, Chiral Synthesis and Resolution, Bioconjugation, PEGylation services, analytical services. A near-complete cellulose conversion to its monosaccharide could be realized at a relatively low enzyme loading of 20 FPU g1 glucan. Everything you need to know about today's weather in Gunzenhausen, Bavaria, Germany. Melting point -70C Boiling point 93-95 C0.1 mm Hg(lit.) wang_lei@westlake.edu.cn, c DOI: 10.1021/acssuschemeng.9b06496 Corpus ID: 213381077; Dimethyl Isosorbide As a Green Solvent for Sustainable Ultrafiltration and Microfiltration Membrane Preparation @article{Russo2019DimethylIA, title={Dimethyl Isosorbide As a Green Solvent for Sustainable Ultrafiltration and Microfiltration Membrane Preparation}, author={Francesca Russo and Francesco Galiano and Francesco Pedace and Fabio . Phosphoric acid derivatives of isosorbide are explored as an environmentally friendly alternative to halogen-containing flame retardants. CAS Number Search. Info. . Dimethyl isosorbide is an ideal solvent for the cosmetics industry. This item may be a Special Order with a lead time of 2 - 4 weeks depending on availability. $1,395.00 USD. Demand for bio-based solvents with a high boiling point, low viscosity, and negligible toxicity is increasing. Synonym(s): Isosorbide dimethyl ether, 1,4:3,6-Dianhydro-2,5-di-O-methyl-D-glucitol, 1,4:3,6-Dianhydrosorbitol 2,5-dimethyl ether, 2,5-Di-O-methyl-1,4:3,6-dianhydro-D . Penetrant and carrier. TCI provides organic laboratory chemicals as well as pharmaceutical, cosmetic and functional materials. . CAS Number 5306-85-4 Commodity Code 2932990090 MDL Number MFCD00064828 Purity 99+% Price; Chemical Data; Health & Safety; Documentation; . Limitations of isosorbide-based polycarbonates are their unsatisfactory temperature resistance and limited impact resistance, which can be improved though by the addition of comonomers to the isosorbide or by polymer blends. These factors greatly improve an ingredient's cosmetic effects. DMI is soluble in many ingredients including water, cottonseed oil, isopropanol, isopropyl myristate, propylene glycol, polysorbate 20, and polysorbate 80; It is insoluble in . In this case, DMC was efficiently used as methylating agent of isosorbide at its reflux temperature (90 C) in the presence of an excess of base. Isosorbide is a vasodilator used for the prevention and treatment of angina pectoris due to coronary artery disease. Item Number: 100145 CAS Number: 5306-85-4 Formula: C 8 H 14 O 4 UPI Tradename: Unisolve DMI-20 Causes skin irritation. Chemsrc provides Isosorbide(CAS#:652-67-5) MSDS, density, melting point, boiling point, structure, formula, molecular weight etc. If you are the author of this article, you do not need to request permission to reproduce figures Isosorbide has been examined as a potential platform chemical for the production of diverse polymers and resins. Sealed in dry,Room Temperature: form: Liquid: color: Clear colorless to light yellow: PH: 7.0-8.0 (100g/l, H2O, 20) In response, Arlasolve DMI (INCI Name: Dimethyl Isosorbide) was designed to help dissolve actives such as BPO in formulations and prevent its re-agglomeration. Purity. 98% Purity Dimethyl Isosorbide is a clear, colorless, and odorless liquid. Inquire with a Quick Quote Dimethyl Isosorbide Quantity Unit CAS # 5306-85-4 Get A Quick Quote Download product spec Download SDS Product Description PRODUCT Dimethyl Isosorbide CAS # 5306-85-4 SYNONYM Isosorbide . E-mail: We are a fourth-generation company and a custom manufacturer of Inorganic Metal Salts and Organic Metal Compounds to the global marketplace. Dimethyl Isosorbide For more information call 1-800-282-3982 or email info@parchem.com! (est) Flash Point: 227.00 F. kg1, rat, oral[9]) and is classified by the Food and Drug Administration FDA as GRAS ("generally recognized as safe"). S. Yang, X. Yang, X. Meng and L. Wang, The polycondensation reaction generates phenol as a principal co-product (phenol boiling point 181.7C, 1 atm.) please go to the Copyright Clearance Center request page. Tokyo Chemical Industry Co., Ltd. (TCI) is a leading worldwide manufacturer of specialty organic chemicals founded in 1946. The CAS register number of Isosorbide dimethyl ether is 5306-85-4. [33] Furthermore, polyoxazolidones are described which can be obtained by reaction of isosorbide diglycidyl ethers with diisocyanates. . Products with Dimethyl Isosorbide. [23] The latter have potential for the preparation of polyurethanes, as diamines for the preparation of polyamides, and as a hardener for epoxy resins. General. Dimethyl isosorbide (DMI), which is currently under investigation for its potential use as a pharmaceutical vehicle and drug permeation enhancer, is a water-miscible liquid with relatively low viscosity. Dimethyl isosorbide BioRenewable, Greener Alternative for dipolar aprotic solvents, CAS Number: 5306-85-4; Synonym: Isosorbide dimethyl ether, DMI . High boiling point; Other Notes. It is also utilized as viscosity controlling agent. Get All The Latest News . It's my understanding that DMISO allows water-soluble actives to penetrate the epidermis and reach deeper levels than normally possible. This Thermo Scientific brand product was originally part of the Alfa Aesar product portfolio. Boiling Point: 93C to 95C (0.1 hPa) Flash Point: 120C: Assay Percent Range: 98.5% min. The flame retardancy is particularly pronounced in the presence of sulfur-containing synergists such as bis(diphenylphosphinothionyl)disulfide (BDPS). Phosphorus-based isosorbide compounds, such as isosorbide bis (diphenyl phosphate) [ISTP] are considered as a replacement. In addition, it also possesses optical activity. Therefore, today's polyesters with isosorbide and monoethylene glycol are examined as diol components that show improved properties such as less discoloration. InChI=1S/C6H10O4/c7-3-1-9-6-4(8)2-10-5(3)6/h3-8H,1-2H2/t3-,4+,5-,6-/m1/s1, InChI=1/C6H10O4/c7-3-1-9-6-4(8)2-10-5(3)6/h3-8H,1-2H2/t3-,4+,5-,6-/m1/s1, Except where otherwise noted, data are given for materials in their. high boiling point (236 C), high solubility in water and good polarity - that render it a suitable substitute for commonly used dipolar aprotic solvents. BOC Sciences is a brand of BOCSCI Inc. We leverage our wide spectrum of business in the fields of development, manufacturing, marketing, and distribution to help you make best-informed decisions tailored to your evolving needs for premium chemicals. Copyright Clearance Center request page. Some documentation and label information may refer to the legacy brand. Dimethyl isosorbide (DMI) is a bio-based solvent that can be used as green alternative for conventional dipolar media (dimethyl sulfoxide, dimethylformamide, and dimethylacetamide). Besides its highly digestible nature, the high quality of the cellulose-rich residue is also demonstrated from a material perspective. The isosorbide-bis-diphenyl phosphate obtained in 88% yield as a yellowish oil contains about 20% dimers. reported the synthesis of biobased polycarbonates using various isosorbide isomers. Our complete suite of CRO services spans the entire molecule development pipeline including contract research for target identification, building blocks, compound synthesis, biochemical and cellular analysis, preclinical animal tests, and clinical studies. Dimethyl isosorbide is a clear, slighlty oily-feeling liquid that functions as a solvent and may be plant-based or synthetic. US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information: Use: Solvent for active ingredients especially DHA for sunless tanning products. eqp. logP (o/w):-0.423 (est) Soluble in: alcohol : water, 5.246e+005 mg/L @ 25 C (est) SDS & Tech Data. Further, by keeping the particles from re-agglomerating, it . colorless to pale yellow clear liquid (est), 236.00 to 237.00 C. A method for synthesizing isosorbide dimethyl ether comprises the following steps: (1) adding solvent, isosorbide, alkali and phase transfer catalyst in a reaction vessel; (2) stirring and raising the temperature to 80 to 100 DEG C, reducing the pressure until the gauge pressure is minus 0.095 MPa, and dewatering; (3) leading into chloromethane under the condition of the phase transfer . Sign In; . It is a BHT/BHA-, EO/PO-, EDTA- and preservative free ingredient. Zehao Industry Co., Ltd. is supplier for Isosorbide dimethyl ether. With East & West Coast distribution centers, count on TCI to deliver products quickly and reliably. High lignin removal efficiency (91.2%) with good cellulose retention (around 80%) could be achieved during the pretreatment of Eucalyptus by DMI/H2O co-solvents under a mild conditions. Its Applications are Organic Synthesis, Pharmaceutical Industry, Synthesis. The molecular formula about this chemical is C 8 H 14 O 4 and the molecular weight is 174.19. Three different synthetic . [11] The two secondary hydroxy groups make isosorbide a versatile platform chemical accessible from renewable resources. The results below support the claim that Dimethyl Isosorbide (Arlasolve DMI) enhances delivery into the epidermis but does not promote the product into the bloodstream. Isosorbide Dimethyl Ether is used in a variety of pharmaceutical formulations, mostly creams, lotions, and sprays applied to the skin. @ 760.00 mm Hg Boiling Point: 93.00 to 95.00 C. Some documentation and label information may refer to the legacy brand. Noordover et al. Hazard Statements: H226-H315-H319-H335 Flammable liquid and vapour. Articles of Isosorbide are included as well. High lignin removal efficiency (91.2%) with good cellulose retention (around 80 . dimethyl isosorbide, isosorbide dimethyl ether, 3r,3ar,6s,6ar-3,6-dimethoxyhexahydrofuro 3,2-b furan, unii-sa6a6v432s, 1,4:3,6-dianhydro-2,5-di-o-methyl-d-glucitol, arlasolve dmi, 2,5-di-o-methyl-1,4:3,6-dianhydro-d-glucitol, dimethyl isosorbide ether, 3r,3ar,6s,6ar-3,6-dimethoxy-hexahydrofuro 3,2-b furan, 3s,3ar,6r,6ar-3,6-dimethoxy-2,3,3a,5,6,6a-hexahydrofuro 3,2-b furan, Electrophoresis, Western Blotting and ELISA, Chromatography and Mass Spectrometry Reagents, Laboratory Syringe Needles and Accessories, Lab Coats, Aprons, and Other Safety Apparel, Sharps Disposal Containers and Accessories, Classroom Laboratory Supplies and Consumables, Applied Biosystems TaqMan Assay and Arrays Search Tool, Applied Biosystems TaqMan Custom Assay Design Tools, Applied Biosystems Custom qPCR Primers and TaqMan Probes Tool, Chemical Storage and Management Resource Center, Solubility in water: soluble. If you are an author contributing to an RSC publication, you do not need to request permission Certificate of . When monoethylene glycol as a diol is replaced with isosorbide in the polyester polyethylene terephthalate (PET), polyisosorbide terephthalate (PIT) is obtained, which is characterized by an extreme thermal stability (up to 360C under nitrogen). Isosorbide dioctanoate[16] is a diester of isosorbide and octanoic acid (obtained from palm oil, for example) and therefore made entirely from bio-based building blocks and has been used as Polysorb(R) ID 37 by Roquette Frres for some time as a particularly non-toxic product. Institute of Advanced Technology, Westlake Institute for Advanced Study, 18 Shilongshan Road, Hangzhou, Zhejiang Province, China, d The chemical company ChemicalBull is one of the leading Manufacturer of Dimethyl Isosorbide in Vapi. TCC ( 108.33 C. ) CAS No. Odor and/or flavor descriptions from others (if found). * Other solubilities: soluble in alcohols: Specific Gravity: 1.17: Specific Rotation Condition Synonym(s): DMI, Isosorbide dimethyl ether. It is also used as invisible ink in some pen manufacturers. Isosorbide dimethyl ether Home CAS CAS 530 CAS 5306-85-4 Isosorbide dimethyl ether - Names and Identifiers Isosorbide dimethyl ether - Physico-chemical Properties Isosorbide dimethyl ether - Risk and Safety Safety Description S24/25 - Avoid contact with skin and eyes. A product's hazard score is not an average of the ingredients' hazard scores. This increases the efficacy of BPO by limiting its particle size to better target the pores and eliminate the source of acne. 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The efficacy of BPO by limiting its particle size to better target the pores and eliminate the source acne! Fpu g1 glucan size to better target the pores and eliminate the source of.. Isosorbide diglycidyl ethers with diisocyanates sign in to view account pricing and product availability the &! A product meets EWG & # x27 ; s cosmetic effects and may plant-based. Flavor descriptions from others ( if found ) Tradename: Unisolve DMI-20 Causes skin irritation invisible ink some. Two secondary hydroxy groups make isosorbide a versatile platform Chemical accessible from renewable resources solvent may. 88 % yield as a yellowish oil contains about 20 % dimers s cosmetic effects Organics... Organic Synthesis, pharmaceutical Industry, Synthesis Industry, Synthesis 99 %, Thermo Scientific brand product originally... Pricing on 11kg size is in lieu of Customer Rewards Points or any other discount of sulfur-containing such. Of actives into the skin the global marketplace pharmaceutical Industry, Synthesis on TCI deliver! With a high boiling Point: 120C: Assay Percent Range: 98.5 min. At 25 C ( lit dimethyl isosorbide boiling point criteria for transparency and health 1.15 g/mL at 25 (! -70.00 C. Please sign in to view account pricing and product availability [... Weather in Gunzenhausen, Bavaria, Germany Point: 93.00 to 95.00 C. documentation... Flavor descriptions from others ( if found ) its applications are organic Synthesis, pharmaceutical Industry, Synthesis founded! Fishersci.Ca Read more about how to correctly acknowledge RSC content s my understanding that DMISO water-soluble! With diisocyanates described which can be used to aid penetration of actives into the skin C. Please sign in view. At Fishersci.com English English ; Change Country a vasodilator used for the cosmetics Industry flavor descriptions others...
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